mcmurry organic chemistry study guide

Chiral Compounds Without Stereocenters It is also possible for a molecule to be chiral without having actual point chirality (stereocenters).
That is because hydrogen is less electronegative than oxygen and gives up its electrons a bit more easily than oxygen does.
Role of nucleophile: SN2 - Good nucleophiles favored SN1 - Any nucleophile will work (since it has no effect on reaction rate) Carbocation stability: 3 carbon - most stable SN1 favored 2 carbon - less stable either could be favored 1 carbon - seldom forms.In a pericyclic reaction, only the bond the klutz book of magic electrons are involved, and all bonds are changed in a single cyclic step without any intermediates being formed.An overall imbalance in charge from one side of a molecule to the other side is called a dipole moment.Note: The X in R-X represents a generic halogen atom.In addition, alkanes have been shown to interact with, and bind to, certain transition metal complexes.The chemistry behind what happened : NaCN - NaCN FeSO4NaCN gives FeCN2 FeCN24NaCN give the complex Na4Fe(CN)6 ferrous oxidizes to ferric by the acid so 3Na4Fe(CN)64Fe3 - Fe4Fe(CN)63.1 p d C P.With cyclo-alkanes, we observe that a group placed on one side of a ring stays on that same side.If a carbon atom (or other type of atom) has four different substituents, that carbon atom forms a chiral center (also known as a stereocenter ).The following laboratory methods can be considered to be in common use for purpose of the preparation of amine compounds: The Gabriel synthesis via azides by the Staudinger reduction.As you can see on the left, the bromine is on the second carbon and in an E1 or E2 reaction, the hydrogen could be removed from either the 1st or the 3rd carbon.Aldehydes and Ketones: Nucleophilic Addition Reactions.Conjugated dienes have conjugated double bonds separated by one single bond Cumulated dienes ( cumulenes ) have the double bonds sharing a common atom as in a group of compounds called allenes.Every stereocenter in one enantiomer has the opposite configuration in the other.The antibiotic only works on peptide links of D-alanine which occur in the cell walls of bacteria - but not in humans.Naming conventions For primary amines, where the amine is not the principal characteristic group, the prefix "amino-" is used.
The structure of benzene emerged during the 1860s, the result of contributions from several chemists, most famously that of Kekulé.
He attended the University of Nebraska at age 14, then three years later transferred to Harvard.




Mole - A measure of a substance that is approximately Avogadro's Number (6.0221023) of molecules of the substance.Experimental alkali metal alternatives that are safer to handle, such as the M-SG reducing agent, also exist.The third would be hard to show but is attached to the same carbon as the red hydrogen, angled a little down from the plane and towards the viewer.The chair conformation (can you see how it looks like a chair?) is lower in energy than the boat conformation.Acid Decarboxylation On heating with sodalime (NaOH/CaO solid mix) carboxylic acids lose their cooh group and produce a small alkane plus sodium carbonate: CH3CH2cooh 2 NaOH CH3CH3 Na2CO3 H2O Note how a carbon is lost from the main chain.Iron(III) bromide and iron(III) chloride lose their catalytic activity if they are hydrolyzed by any moisture present, including atmospheric water vapor.These two things happen in a single step.Electron Withdrawing Groups On monosubstituted rings, electron donating groups resonate at high chemical shifts.Trans isomers generally have higher boiling points and lower densities.The Study of Organic Chemistry, organic chemistry is primarily devoted to the unique properties of the carbon atom and its compounds.That is, in a Newman projection, the H and X must be 180, or in the anti-configuration.
Indeed, in tetrahydrofuran, one of the solvents used for hydroboration, the reagent exists as the monomer, in the form of an acid-base complex with the solvent.